The gradual wear of the occlusal surfaces of teeth is a normal process during the lifetime of a patient. However, excessive occlusal wear can result in pulpal pathology, occlusal disharmony, impaired function, and esthetic disfigurement. Most common treatment modality for this scenario is full mouth rehabilitation. Occlusal harmony is essential in any full mouth rehabilitation. Occlusion is a decisive factor for oral health and TMJ. For many years, articulating paper has been the gold standard for assessing occlusal contacts. The paper leaves marks of occlusal contacts. However, salivary interference is present. In contrast, T-scan gave a more precise and visual representation of the occlusal contacts with multiple color indicators for various percentages of pressure. Its sensor also works independent of salivary interference and gives a more precise representation of the occlusal contacts in full mouth rehabilitation. One of the most common complaints in full mouth rehabilitation cases is the decementation of the crowns. Having successfully negotiated the planning, preparation, impression and fabrication of the crowns, the cementation stage represents the final culmination of the full mouth rehabilitation. However, there are no studies available how the occlusal calibration affects the retention of crowns. Thus, the purpose of this study was to assess the rate of decementation of crowns when occlusal calibration was performed with T-scan and articulating paper in an 18 month follow up. 7 patients were lost during followup. Only 73 patients reported for the 18 month follow up out of 80 patients, 36 in Group A and 37 in Group B. The patient drop out rate was within the expected attrition rate of 20%. At the patient level, 11 patients reported with decementation out of 36 in Group A while 5 patients reported with decementation out of 37 in Group B. At the crown level, Loss of retention was seen in 15 crowns out of 1008 crowns in Group A while loss of retention was seen in 6 crowns out of 1036 crowns in Group B. Data was analysed using SPSS version 20.0 (IBM, India, trial version). The statistical analyses were performed using independent samples t-test to determine statistical significance. The results show that there is a significant difference in the rate of decementation of crowns in full mouth rehabilitated patients when occlusal analysis is done with T-Scan and articulating paper in an 18 month follow up period both at patient and crown level.

It is now generally known that English is used as an international language of science (EILS). Depending on one's perspective, English may be viewed as a neutral lingua franca or, more sinisterly, as a dominating and overpowering force. This essay examines these concurrent roles of EILS from a number of angles. It starts out by describing discussions about EILS that have been published in applied linguistics literature and in the scientific community. The research then shifts to the viewpoint of foreign graduate students attending an American university through a small-scale survey and focus group interview study that aims to comprehend these students' perspectives toward English and its function in scientific communication. The study's results and their significance for an EAP classroom that seeks to acknowledge the dual roles of English in scientific communication are examined in light of published discussions of EILS.

Since 2010, matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF MS) has been used in healthcare settings. Over the traditional method of biochemical identification, MALDI-TOF MS has a number of advantages, including simplicity, speed, precision, and affordability. Numerous challenges to detecting bacteria, fungi, and viruses can be overcome using this method. As technology developed, a growing number of databases tracked spectra, enabling the identification of species that had similar morphological, genotypic, and biochemical features. Due to improvements in sample preparation and database enrichment, using MALDI-TOF MS for identification has become more precise and rapid. MALDI-TOF MS has yielded encouraging results for colony identification and quick sample detection. Rapidly diagnosing extremely contagious and drug- resistant illnesses is a crucial use of MALDI-TOF MS. Here, we give a review of the scientific literature evaluating the efficiency of MALDI-TOF MS for identifying pathogenic bacteria, fungi, and viruses that are relevant to clinical settings. Although MALDI-TOF MS offers several advantages for finding clinical infections, it also has significant disadvantages. Because there aren't many spectra in the database and organisms have inherent similarities, it might be challenging to tell one species from another, leading to misidentifications. Additional testing is typically necessary to fix these issues, which are extremely rare. In conclusion, the use of MALDI-TOF is revolutionising the detection and treatment of infectious diseases.

Heart Rate Variability (HRV) is commonly used to assess autonomic functions and responses to environmental stimuli. It is usually derived from electrocardiographic signals; however, in the last few years, photoplethysmography has been successfully used to evaluate beat-to-beat time intervals and to assess changes in the human heart rate under several conditions. The present work describes a simple design of a photoplethysmography, using a wearable earlobe sensor. Beat-to-beat time intervals were evaluated as the time between subsequent pulses,

thus generating a signal representative of heart rate variability, which was compared to RR intervals from classic electrocardiography.

Background: Individuals with bipolar disorder (BD) are known to have worse physical health and reduced life expectancy compared to the general population. Excess cardiovascular mortality in BD is partly attributed to metabolic syndrome and diabetes mellitus (DM), which both occur with higher-than-expected prevalence’s in this population (37.3–41.1% and 26 % respectively). Patients with comorbid BD and DM type 2 or insulin resistance have greater morbidity, lower treatment response, greater chronicity, and disability, as well as more prominent brain structure alterations. To compare the largest set of bipolar disorder pharmacotherapies to date for risk of diabetes mellitus (DM).

Materials and methods: In this study, we used electronic data available for all VHA patients nationally (51). This includes information on all VHA medical encounters (outpatient, inpatient, and long-term-care) obtained from the Austin Automation Center, VHA outpatient and inpatient prescription data from the Hospital, and death records from the Beneficiary Identification Records Locator Subsystem, a registry of all veterans who applied for VHA death benefits that is supplemented by data from Social Security records.

Result: We observed 140 patients in the four cohorts of antipsychotic initiators studied (table 1). Patients in these cohorts were broadly similar in terms of age, sex, race/ ethnicity, marital status, use of other potentially diabetogenic medications, and number of diabetes screening tests. There were slightly more women and fewer racial minority patients among the quetiapine users, and more never-married and Indian patients among those prescribed haloperidol. Otherwise, frequency distributions varied by no more than a few percentage points across the four cohorts. Average length of follow-up was also similar (just over 1 year), except for quetiapine, which was only approved for use during the study. The annual incidence (unadjusted) of new-onset diabetes over the course of follow-up ranged from 4.0 per 100 person-years of exposure in users of haloperidol to 5.8 per 100 person-years in quetiapine users.

Conclusion: Schizophrenia confers a high endogenous risk for diabetes, and the risk is further increased by both first generation and second-generation antipsychotics. Early detection and effective treatment of diabetes should be an integral part of multidisciplinary management of schizophrenia regardless of antipsychotic drug exposure.

Background: Placenta is a functional unit between the mother and the fetus. It is the discoid, deciduate, hemochorial, chorioallantoic, endocrine gland which connects developing embryo by umbilical cord to the uterus. It develops from two sources. The fetal component which is the principal component develops from chorion frondosum and the maternal component from decidua basalis. If the decidual part of the placenta is healthy, the embryogenesis from germinal period up to the end of fetal period will be healthy. Material and Methods: This is a prospective and observational study conducted in the Department of Anatomy at Tertiary care Teaching Hospital from April 2021 to December 2021. Inclusion Criteria: Totally, 90 healthy mothers who gave birth to uncomplicated singleton pregnancy, and their new-born were included in the study. Exclusion Criteria: Subjects with diabetes mellitus, hypertension, anaemia, vascular diseases, and multiple pregnancies were excluded from this study. Results: In present study, newborn body mass index (BMI in kg/m2) was measured. Majority (55.55%) of the newborn were within BMI range of 11-13 kg/m2 followed by 25.57% of the new-born were with BMI >14 kg/m2 and the lesser proportion of 18.88% new- born with BMI <10 kg/m2. The mean placental weight (in gms) for female babies with BMI <10 kg/m2 was 402.23±56.81. The mean placental weight (in gms) for male and female babies with BMI 11-13 kg/m2 were 421.35±58.67 and 501.28±60.84 respectively. In addition, mean placental weight (in gms) for male and female babies with BMI >14 kg/m2 were 569.54±54.37 and 556.76±67.91 respectively. The mean placental diameter (in cms) for female babies with BMI <10 kg/m2 was 19.23±2.68. The mean placental diameter (in cms) for male and female babies were 20.89±2.87 and 21.58±2.76 respectively with BMI of 11-13 kg/m2. Moreover, mean placental diameter (in cms) for male and female babies were 22.61±2.93 and 20.97±2.99 respectively with BMI of >14 kg/m2.Conclusion:This study confirms that morphometric observation of placenta is associated with foetal weight. So, an early examination of not only the fetus, but also the placenta by non-invasive techniques like ultrasonography will be helpful to predict and to avoid low birth weight babies with better preventive measures. This study will also help the obstetricians and researchers to focus on the impact of placenta on new-born BMI.

In spite of efforts to combat it, malaria in India continues to be a major threat to public health. Future trends in Malaria-related mortality in India were predicted using the Autoregressive Integrated Moving Average (ARIMA) model. We ran crucial diagnostic tests, including the Augmented Dickey-Fuller (ADF) test, the Autocorrelation Function (ACF), the Partial Autocorrelation Function (PACF), and the Box- Jenkins approach, to make sure the model was accurate. The stationarity of the time series data and the optimal ARIMA model parameters could then be determined with the use of these tests. We were able to build a reliable forecasting model that sheds light on the future of Malaria-related mortality in India by combining various analytical tools. This study's findings will help in the development of preventative strategies and focused treatments to lessen the impact of Malaria in the country.

Traditional system in cryptography allows just sharing of keys between the sender and receiver, for such a technique only the signature storage is provided for the user’s public key. But as the number of users increases, it’s became a challenging job to have such a certificate storage as well as key distribution, to overcome this Identity Based Encryption (IBE) was proposed, but again it had created the time consuming environment as it was supporting only to one-to-one communication. After IBE Attribute Based encryption (ABE) made possibility to provide multicast communication between users but it was limited to only key policy based encryption as well as could not provide the revocation phenomenon for keys. So this paper aims to develop an existing system using MAMM (Multiple Authority Multiple Mediator) with the use of distributed CP-ABE(Cipher Policy ABE) which enhances the revocation and improves the performance

Introduction: Appendix is connected by a short mesoappendix to the lower part posterior (left)layer of the ileal mesentery. This fold is usually triangular, extending almost to the appendicular tip along the whole tube. The mesoappendix has a free border which carries the blood supply to the organ, by the appendicular artery; a branch from the ileocolic artery. This study has been undertaken to investigate certain anatomical features such as the extent of the mesoappendix

Material and method: This study was conducted on 91 cases from the dissection laboratory with an age range of 50-90 years, The dissection was performed in dissection hall of various medical collage of Ahmedabad.

Result: In present study mesoappendix was not reach at tip of vermiform appendix in 50cases (54.95%) and mesoappendix is reach at tip of vermiform appendix in 65cases (45.05%).

Conclusion: Appendix is supplied by aend artery which is one of cause of occurrence of appendicitis. Appendicular artery which is branch of inferior division of iliocolic artery which goes through appendix along mesoappendix. In the present study variation in length of mesoappendix was seen from which we can understand about blood supply and vascularity of appendix. The appendicular artery runs first in the free margin of the mesoappendix and then.

close to the appendicular wall, where it may be thrombosed in appendicitis, leading to ischemic necrosis and perhaps rupture of the appendix, there is no collateral circulation for appendicular artery is an end artery.