The gradual wear of the occlusal surfaces of teeth is a normal process during the lifetime of a patient. However, excessive occlusal wear can result in pulpal pathology, occlusal disharmony, impaired function, and esthetic disfigurement. Most common treatment modality for this scenario is full mouth rehabilitation. Occlusal harmony is essential in any full mouth rehabilitation. Occlusion is a decisive factor for oral health and TMJ. For many years, articulating paper has been the gold standard for assessing occlusal contacts. The paper leaves marks of occlusal contacts. However, salivary interference is present. In contrast, T-scan gave a more precise and visual representation of the occlusal contacts with multiple color indicators for various percentages of pressure. Its sensor also works independent of salivary interference and gives a more precise representation of the occlusal contacts in full mouth rehabilitation. One of the most common complaints in full mouth rehabilitation cases is the decementation of the crowns. Having successfully negotiated the planning, preparation, impression and fabrication of the crowns, the cementation stage represents the final culmination of the full mouth rehabilitation. However, there are no studies available how the occlusal calibration affects the retention of crowns. Thus, the purpose of this study was to assess the rate of decementation of crowns when occlusal calibration was performed with T-scan and articulating paper in an 18 month follow up. 7 patients were lost during followup. Only 73 patients reported for the 18 month follow up out of 80 patients, 36 in Group A and 37 in Group B. The patient drop out rate was within the expected attrition rate of 20%. At the patient level, 11 patients reported with decementation out of 36 in Group A while 5 patients reported with decementation out of 37 in Group B. At the crown level, Loss of retention was seen in 15 crowns out of 1008 crowns in Group A while loss of retention was seen in 6 crowns out of 1036 crowns in Group B. Data was analysed using SPSS version 20.0 (IBM, India, trial version). The statistical analyses were performed using independent samples t-test to determine statistical significance. The results show that there is a significant difference in the rate of decementation of crowns in full mouth rehabilitated patients when occlusal analysis is done with T-Scan and articulating paper in an 18 month follow up period both at patient and crown level.